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Query: DDX42

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX42 0 1.152 -1.180 1.640 0.239 -0.028 -0.479 -0.132 0.059

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX42 Phosphorylation S754 -0.014 _AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDS(ph)PVTSAAK_
DDX42 Phosphorylation S185 -0.524 -0.498 _YMAENPTAGVVQEEEEDNLEYDS(ph)DGNPIAPTKK_
DDX42 Phosphorylation Y183 -0.599 -0.570 _YMAENPTAGVVQEEEEDNLEY(ph)DSDGNPIAPTKK_
DDX42 Phosphorylation S96 -0.133 -0.665 _RANFDEENAYFEDEEEDSSNVDLPYIPAENS(ph)PTR_
DDX42 Phosphorylation T98 -0.418 -1.050 _RANFDEENAYFEDEEEDSSNVDLPYIPAENS(ph)PTR_

Background Information for DDX42:


Pubmed-DDX42 »
Uniprot-DDX42 »
Biogrid-DDX42 »
ProteomicsDB-DDX42 »

Tumorportal-DDX42 »
COSMIC-DDX42 »
GenomeRNAi-DDX42 »
Genecards-DDX42


Protein-protein Interactions for DDX42
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AFF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ITGB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF13B Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRIF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGEA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX42
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members RNA_helicase_DEAD_Q_motif IPR014014 0.24


Protein complexes (CORUM database) featuring DDX42
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1737 SF3b complex Database 0.08


Categories featuring DDX42
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0008104 protein localization Database 0.5
Category members GO Category GO:0015030 Cajal body Database 0.04


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