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Query: DDX21

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX21 2 4.257 0.130 -0.120 -0.288 -0.093 0.027 -0.154 0.016

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX21 Ubiquitylation K779 0.976 2.093 _SFSK(gl)AFGQ_
DDX21 Ubiquitylation K481 1.165 1.547 _EITLK(gl)GFR_
DDX21 Ubiquitylation K285 1.226 0.621 _DFSDITK(gl)K_
DDX21 Phosphorylation S13 0.368 0.556 _SDAGLES(ph)DTAMK_
DDX21 Ubiquitylation K448 0.296 _TIIFCETK(gl)K_
DDX21 Ubiquitylation K449 0.296 _TIIFCETK(gl)K_
DDX21 Phosphorylation S89 -0.313 -0.086 _KKEEPSQNDIS(ph)PK_
DDX21 Phosphorylation S121 -0.428 -0.293 _NEEPS(ph)EEEIDAPKPK_
DDX21 Phosphorylation S71 -1.693 -0.964 _KKAEPSEVDMNS(ph)PK_
DDX21 Ubiquitylation K403 1.118 _STYEQVDLIGKK(gl)_
DDX21 Ubiquitylation K406 1.732 _TQK(gl)TAITVEHLAIK_
DDX21 Ubiquitylation K676 1.139 _GMVFLK(gl)GK_

Background Information for DDX21:


Pubmed-DDX21 »
Uniprot-DDX21 »
Biogrid-DDX21 »
ProteomicsDB-DDX21 »

Tumorportal-DDX21 »
COSMIC-DDX21 »
GenomeRNAi-DDX21 »
Genecards-DDX21


Protein-protein Interactions for DDX21
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DLG5 Cat. description Hein, Mann, Cell 2015
Category members IP bait EED Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPATCH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MKI67IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL37A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNCRIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF512 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX21
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Helicase/UvrB_dom IPR006935 0.78
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members GUCT IPR012562 0


Protein complexes (CORUM database) featuring DDX21
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3055 Nop56p-associated pre-rRNA complex Database INF
Category members Corum 924 Toposome Database 0.88


Categories featuring DDX21
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0003725 double-stranded RNA binding Database 0.1
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0043330 response to exogenous dsRNA Database 0


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