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Query: CYP51A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CYP51A1 0 2.000 0.435 0.502

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CYP51A1 Ubiquitylation K266 0.573 _DIFYK(gl)AIQK_
CYP51A1 Ubiquitylation K368 0.490 0.247 _CIK(gl)ETLR_
CYP51A1 Ubiquitylation K412 -0.492 0.017 _LK(gl)DSWVER_
CYP51A1 Ubiquitylation K156 -0.292 _GVAYDVPNPVFLEQK(gl)K_
CYP51A1 Ubiquitylation K157 0.360 -0.309 _GVAYDVPNPVFLEQKK(gl)_
CYP51A1 Ubiquitylation K436 -0.295 -0.462 _YLQDNPASGEK(gl)FAYVPFGAGR_

Background Information for CYP51A1:


Pubmed-CYP51A1 »
Uniprot-CYP51A1 »
Biogrid-CYP51A1 »
ProteomicsDB-CYP51A1 »

Tumorportal-CYP51A1 »
COSMIC-CYP51A1 »
GenomeRNAi-CYP51A1 »
Genecards-CYP51A1


Protein-protein Interactions for CYP51A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CYP51A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CYP51A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyt_P450 IPR001128 0.23
Category members Cyt_P450_E_grp-I IPR002401 0.23
Category members Cyt_P450_E_grp-IV IPR002403 0.23
Category members Cyt_P450_B IPR002397 0.14


Protein complexes (CORUM database) featuring CYP51A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CYP51A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_159 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE 0 0.34
Category members GO Category GO:0006694 steroid biosynthetic process Database 0.29
Category members GO Category GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Database 0.05
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0020037 heme binding Database 0.04
Category members Pathway Pathway_141 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 0 0
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_163 REACTOME_ENDOGENOUS_STEROLS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0016125 sterol metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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