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Query: CWC22

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CWC22 1 5.006 -2.870 5.920 -1.138 -0.403 -0.233

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CWC22 Phosphorylation S829 0.483 0.377 _RNS(ph)FSENEK_

Background Information for CWC22:


Pubmed-CWC22 »
Uniprot-CWC22 »
Biogrid-CWC22 »
ProteomicsDB-CWC22 »

Tumorportal-CWC22 »
COSMIC-CWC22 »
GenomeRNAi-CWC22 »
Genecards-CWC22


Protein-protein Interactions for CWC22
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CTBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTDSP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERMAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FMR1NB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR183 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CWC22
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members MIF4G-like_typ-3 IPR003890 0
Category members Initiation_fac_eIF4g_MI IPR003891 0


Protein complexes (CORUM database) featuring CWC22
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring CWC22
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0048024 regulation of mRNA splicing, via spliceosome Database 0


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