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Query: CTTN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTTN 0 3.359 0.900 0.000 0.303 0.658 -0.157

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CTTN Phosphorylation S150 0.128 0.953 _HAS(ph)QKDYSSGFGGK_
CTTN Phosphorylation S447 -1.103 0.639 _GPVSGTEPEPVYS(ph)MEAADYR_
CTTN Phosphorylation S418 0.897 0.444 _LPSS(ph)PVYEDAASFK_
CTTN Phosphorylation S405 -0.318 -0.627 _TQT(ph)PPVS(ph)PAPQPTEER_
CTTN Phosphorylation S417 1.028 -0.653 _TQT(ph)PPVS(ph)PAPQPTEERLPS(ph)SPVYEDAASFK_
CTTN Phosphorylation T411 -1.196 -1.112 _TQT(ph)PPVSPAPQPT(ph)EERLPSSPVYEDAASFK_
CTTN Phosphorylation T401 -1.594 -1.336 _TQT(ph)PPVSPAPQPTEER_
CTTN Phosphorylation T399 -0.214 -1.441 _AKT(ph)QTPPVS(ph)PAPQPTEER_
CTTN Phosphorylation Y421 -1.514 _T(ph)QTPPVSPAPQPTEERLPSSPVY(ph)EDAASFK_
CTTN Ubiquitylation K110 0.305 _LSK(gl)HCSQVDSVR_
CTTN Ubiquitylation K152 0.237 _HASQK(gl)DYSSGFGGK_
CTTN Ubiquitylation K193 0.574 _DYSK(gl)GFGGK_

Background Information for CTTN:


Pubmed-CTTN »
Uniprot-CTTN »
Biogrid-CTTN »
ProteomicsDB-CTTN »

Tumorportal-CTTN »
COSMIC-CTTN »
GenomeRNAi-CTTN »
Genecards-CTTN


Protein-protein Interactions for CTTN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015


Protein Domains in CTTN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Hs1_Cortactin IPR003134 0


Protein complexes (CORUM database) featuring CTTN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5318 DDEF1-CTTN-PXN complex Database 0.35
Category members Corum 1130 Hip1R-cortactin complex Database 0


Categories featuring CTTN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0043197 dendritic spine Database 0.86
Category members Pathway Pathway_1074 PID_SYNDECAN_3_PATHWAY 0 0.65
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_1026 KEGG_PATHOGENIC_ESCHERICHIA_COLI_INFECTION 0 0.45
Category members GO Category GO:0001726 ruffle Database 0.33
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members Pathway Pathway_1041 BIOCARTA_AGR_PATHWAY 0 0.13
Category members Pathway Pathway_657 PID_FGF_PATHWAY 0 0


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