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Query: CTPS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTPS1 1 2.794 0.800 -0.420 -0.335 1.508 -0.510 0.616 0.378

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CTPS1 Ubiquitylation K84 0.695 _LTK(gl)DNNLTTGK_
CTPS1 Ubiquitylation K381 -0.086 0.306 _GTEGK(gl)IQAIAWAR_
CTPS1 Phosphorylation S575 0.142 -0.002 _SGSSS(ph)PDSEITELK_
CTPS1 Phosphorylation S574 -0.085 -0.063 _SGSS(ph)SPDSEITELKFPSINHD_
CTPS1 Phosphorylation S571 -0.129 -0.106 _S(ph)GSSSPDSEITELKFPSINHD_
CTPS1 Ubiquitylation K460 -0.506 -0.464 _TLFQTK(gl)NSVMR_
CTPS1 Ubiquitylation K490 0.302 _K(gl)CLEEQGLK_
CTPS1 Phosphorylation S578 -0.269 _SGSSSPDS(ph)EITELKFPSINHD_

Background Information for CTPS1:


Pubmed-CTPS1 »
Uniprot-CTPS1 »
Biogrid-CTPS1 »
ProteomicsDB-CTPS1 »

Tumorportal-CTPS1 »
COSMIC-CTPS1 »
GenomeRNAi-CTPS1 »
Genecards-CTPS1


Protein-protein Interactions for CTPS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNX3 Cat. description Hein, Mann, Cell 2015


Protein Domains in CTPS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members CTP_synthase IPR004468 0.08
Category members CTP_synthase_N IPR017456 0.08
Category members GATASE IPR017926 0.04
Category members Peptidase_C26 IPR011697 0.04
Category members Class_I_gatase-like IPR029062 0


Protein complexes (CORUM database) featuring CTPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0003883 CTP synthase activity Database 0.08
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0044210 'de novo' CTP biosynthetic process Database 0.08
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0006221 pyrimidine nucleotide biosynthetic process Database 0
Category members GO Category GO:0006241 CTP biosynthetic process Database 0
Category members GO Category GO:0015949 nucleobase-containing small molecule interconversion Database 0
Category members GO Category GO:0055086 nucleobase-containing small molecule metabolic process Database 0


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