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Query: COPS8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
COPS8 1 4.255 -2.510 4.680 -0.425

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for COPS8:


Pubmed-COPS8 »
Uniprot-COPS8 »
Biogrid-COPS8 »
ProteomicsDB-COPS8 »

Tumorportal-COPS8 »
COSMIC-COPS8 »
GenomeRNAi-COPS8 »
Genecards-COPS8


Protein-protein Interactions for COPS8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait FBL Cat. description Hein, Mann, Cell 2015
Category members IP bait BMX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in COPS8
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring COPS8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 728 CSA-POLIIa complex Database 1.74
Category members Corum 726 DDB2 complex Database 1.33
Category members Corum 727 CSA complex Database 1.33
Category members Corum 2715 Ubiquitin E3 ligase (CSN1, CSN8, HRT1, SKP1, SKP2, CUL1, CUL2, CUL3) Database 0.61
Category members Corum 2174 COP9 signalosome complex Database 0.48
Category members Corum 2179 CNS-P53 complex Database 0.19


Categories featuring COPS8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0010388 cullin deneddylation Database 0.25


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