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Query: COPS3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
COPS3 0 3.773 1.000 -0.850 -0.060 0.717 0.043

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
COPS3 Phosphorylation S410 0.685 1.334 _SM(ox)GS(ph)QEDDSGNKPSSYS_
COPS3 Phosphorylation S407 1.311 _S(ph)MGSQEDDSGNKPSSYS_
COPS3 Ubiquitylation K281 0.168 0.593 _NLVNK(gl)HSETFTR_
COPS3 Ubiquitylation K125 0.384 _GIGILK(gl)QAIDK_
COPS3 Phosphorylation S423 0.370 0.214 _SMGSQEDDSGNKPSSYS(ph)_
COPS3 Ubiquitylation K391 0.160 -0.420 _LK(gl)AMDQEITVNPQFVQK_
COPS3 Ubiquitylation K296 0.462 _DNNMGLVK(gl)QCLSSLYK_

Background Information for COPS3:


Pubmed-COPS3 »
Uniprot-COPS3 »
Biogrid-COPS3 »
ProteomicsDB-COPS3 »

Tumorportal-COPS3 »
COSMIC-COPS3 »
GenomeRNAi-COPS3 »
Genecards-COPS3


Protein-protein Interactions for COPS3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait COPS7A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DDB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait LRR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DET1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in COPS3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PCI_dom IPR000717 2.22


Protein complexes (CORUM database) featuring COPS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 728 CSA-POLIIa complex Database 1.74
Category members Corum 726 DDB2 complex Database 1.33
Category members Corum 727 CSA complex Database 1.33
Category members Corum 2174 COP9 signalosome complex Database 0.48
Category members Corum 2179 CNS-P53 complex Database 0.19


Categories featuring COPS3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0010388 cullin deneddylation Database 0.25
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0009416 response to light stimulus Database 0.06
Category members GO Category GO:0007165 signal transduction Database 0


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