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Query: CLCN7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLCN7 1 0.221 0.900 -0.600 0.461 -0.162

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLCN7 Phosphorylation S60 -0.795 -0.945 _VGHMS(ph)SVELDDELLDPDMDPPHPFPK_
CLCN7 Phosphorylation S61 -0.795 -0.997 _VGHMSS(ph)VELDDELLDPDMDPPHPFPK_
CLCN7 Ubiquitylation K6 1.497 _(ac)ANVSK(gl)K(gl)VSWSGR_
CLCN7 Ubiquitylation K7 1.662 _K(gl)VSWSGR_

Background Information for CLCN7:


Pubmed-CLCN7 »
Uniprot-CLCN7 »
Biogrid-CLCN7 »
ProteomicsDB-CLCN7 »

Tumorportal-CLCN7 »
COSMIC-CLCN7 »
GenomeRNAi-CLCN7 »
Genecards-CLCN7


Protein-protein Interactions for CLCN7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM46A Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BIRC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM177A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBLAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCOLN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLCN7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CBS_dom IPR000644 0
Category members Cl-channel_volt-gated IPR001807 0
Category members Cl-channel_core IPR014743 0


Protein complexes (CORUM database) featuring CLCN7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLCN7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005216 ion channel activity Database 0.16
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0009268 response to pH Database 0.01
Category members Disease phenotype Autosomal_recessive_malignant_osteopetrosis Autosomal recessive malignant osteopetrosis Database 0
Category members Disease phenotype Intermediate_osteopetrosis Intermediate osteopetrosis Database 0
Category members GO Category GO:0005247 voltage-gated chloride channel activity Database 0
Category members GO Category GO:0005254 chloride channel activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006821 chloride transport Database 0
Category members GO Category GO:0015297 antiporter activity Database 0
Category members GO Category GO:0030554 adenyl nucleotide binding Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0


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