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Query: CLCN6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLCN6 1 0.792 2.010 -1.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLCN6 Ubiquitylation K679 -0.037 0.829 _SQSMK(gl)SYPSSELR_

Background Information for CLCN6:


Pubmed-CLCN6 »
Uniprot-CLCN6 »
Biogrid-CLCN6 »
ProteomicsDB-CLCN6 »

Tumorportal-CLCN6 »
COSMIC-CLCN6 »
GenomeRNAi-CLCN6 »
Genecards-CLCN6


Protein-protein Interactions for CLCN6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6V0A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLCN6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CBS_dom IPR000644 0
Category members Cl-channel_volt-gated IPR001807 0
Category members Cl-channel_core IPR014743 0


Protein complexes (CORUM database) featuring CLCN6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLCN6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0009612 response to mechanical stimulus Database 0.23
Category members GO Category GO:0005216 ion channel activity Database 0.16
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0005247 voltage-gated chloride channel activity Database 0
Category members GO Category GO:0006821 chloride transport Database 0
Category members GO Category GO:0006884 cell volume homeostasis Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0015297 antiporter activity Database 0
Category members GO Category GO:0030554 adenyl nucleotide binding Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0


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