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Query: CHTOP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHTOP 2 3.055 -0.080 -0.160 0.030 -0.136 -0.592 0.338

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHTOP Ubiquitylation K226 2.163 _EQLDNQLDAYMSK(gl)TK_
CHTOP Ubiquitylation K81 0.939 _LGK(gl)SNIQAR_
CHTOP Phosphorylation T33 -0.582 -0.320 _NKQPT(ph)PVNIR_
CHTOP Ubiquitylation K16 2.153 _STTK(gl)MSLNER_
CHTOP Ubiquitylation K28 1.618 _FTNMLK(gl)NK_
CHTOP Ubiquitylation K30 1.618 _FTNMLK(gl)NK_
CHTOP Ubiquitylation K70 0.849 _LAQQMENRPSVQAALK(gl)LK_
CHTOP Ubiquitylation K213 1.034 _PVLTK(gl)EQLDNQLDAYMSK_
CHTOP Ubiquitylation K228 1.831 _EQLDNQLDAYMSKTK(gl)_

Background Information for CHTOP:


Pubmed-CHTOP »
Uniprot-CHTOP »
Biogrid-CHTOP »
ProteomicsDB-CHTOP »

Tumorportal-CHTOP »
COSMIC-CHTOP »
GenomeRNAi-CHTOP »
Genecards-CHTOP


Protein-protein Interactions for CHTOP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCLAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPIRE2 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC7 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHCHD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FYTTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LBR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSPO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SARNP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF13B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CHTOP
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CHTOP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CHTOP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0000346 transcription export complex Database 1.18
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0051096 positive regulation of helicase activity Database 0.73
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0032781 positive regulation of ATPase activity Database 0


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