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Query: CERS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CERS2 0 1.415 0.540 -0.590 0.176 0.286

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CERS2 Ubiquitylation K96 -0.388 1.140 _QPK(gl)QVEVELLSR_
CERS2 Ubiquitylation K132 -0.187 0.184 _NQDRPSLLKK(gl)_
CERS2 Ubiquitylation K131 -0.387 _NQDRPSLLK(gl)K_

Background Information for CERS2:


Pubmed-CERS2 »
Uniprot-CERS2 »
Biogrid-CERS2 »
ProteomicsDB-CERS2 »

Tumorportal-CERS2 »
COSMIC-CERS2 »
GenomeRNAi-CERS2 »
Genecards-CERS2


Protein-protein Interactions for CERS2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in CERS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members TLC-dom IPR006634 0
Category members Homeodomain-like IPR009057 0
Category members Longevity_assurance_LAG1_LAC1 IPR016439 0


Protein complexes (CORUM database) featuring CERS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CERS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_128 REACTOME_SPHINGOLIPID_METABOLISM 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_498 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS 0 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006665 sphingolipid metabolic process Database 0
Category members GO Category GO:0030148 sphingolipid biosynthetic process Database 0
Category members GO Category GO:0046513 ceramide biosynthetic process Database 0
Category members GO Category GO:0050291 sphingosine N-acyltransferase activity Database 0


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