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Query: CEP76

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CEP76 0 0.505 -0.270 0.460

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CEP76 Phosphorylation S83 -0.021 0.066 _ELNFVTDSVEQELPSS(ph)PKQPICFDR_

Background Information for CEP76:


Pubmed-CEP76 »
Uniprot-CEP76 »
Biogrid-CEP76 »
ProteomicsDB-CEP76 »

Tumorportal-CEP76 »
COSMIC-CEP76 »
GenomeRNAi-CEP76 »
Genecards-CEP76


Protein-protein Interactions for CEP76
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP76 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FHL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSPO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WIPI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CEP76
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members C2_dom IPR000008 0


Protein complexes (CORUM database) featuring CEP76
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CEP76
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0005814 centriole Database 0
Category members GO Category GO:0046599 regulation of centriole replication Database 0


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