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Query: CDKL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDKL1 0 -0.477 -0.310 -0.290

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDKL1 Ubiquitylation K33 -0.187 _DTGQIVAIK(gl)K_
CDKL1 Ubiquitylation K34 -0.187 _DTGQIVAIK(gl)K_

Background Information for CDKL1:


Pubmed-CDKL1 »
Uniprot-CDKL1 »
Biogrid-CDKL1 »
ProteomicsDB-CDKL1 »

Tumorportal-CDKL1 »
COSMIC-CDKL1 »
GenomeRNAi-CDKL1 »
Genecards-CDKL1


Protein-protein Interactions for CDKL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDKL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDKL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDKL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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