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Query: CDK3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK3 0 3.183 -1.270 2.210 -0.578 -0.797

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK3 Phosphorylation Y15 0.697 0.743 _IGEGTY(ph)GVVYK_
CDK3 Ubiquitylation K34 0.542 _LTGEVVALKK(gl)_
CDK3 Ubiquitylation K20 0.272 _IGEGTYGVVYK(gl)AR_
CDK3 Ubiquitylation K33 0.033 _NKLTGEVVALK(gl)K_
CDK3 Ubiquitylation K6 -0.130 -0.399 _(ac)MENFQK(gl)VEK_
CDK3 Ubiquitylation K298 -1.907 -2.380 _QDFSK(gl)VVPPLDEDGR_
CDK3 Phosphorylation T14 0.429 _IGEGT(ph)YGVVYK_
CDK3 Ubiquitylation K24 0.366 _NK(gl)LTGEVVALKK_

Background Information for CDK3:


Pubmed-CDK3 »
Uniprot-CDK3 »
Biogrid-CDK3 »
ProteomicsDB-CDK3 »

Tumorportal-CDK3 »
COSMIC-CDK3 »
GenomeRNAi-CDK3 »
Genecards-CDK3


Protein-protein Interactions for CDK3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait B3GNT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCNA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CKS1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0045023 G0 to G1 transition Database 0


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