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Query: CDK18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK18 0 1.611 0.240 0.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK18 Phosphorylation S132 0.615 0.596 _RASLS(ph)DIGFGK_
CDK18 Phosphorylation S87 0.561 _RFS(ph)MEDVSK_
CDK18 Phosphorylation S130 0.568 0.506 _RAS(ph)LSDIGFGK_
CDK18 Ubiquitylation K221 0.400 _LTENLVALK(gl)EIR_
CDK18 Phosphorylation S96 0.155 _RLS(ph)LPMDIR_
CDK18 Phosphorylation S12 0.169 0.071 _RFS(ph)LSVPR_
CDK18 Ubiquitylation K212 -0.028 _SK(gl)LTENLVALK_
CDK18 Phosphorylation S72 -1.257 _DPPQECSTFSPTDSGEEPGQLS(ph)PGVQFQR_

Background Information for CDK18:


Pubmed-CDK18 »
Uniprot-CDK18 »
Biogrid-CDK18 »
ProteomicsDB-CDK18 »

Tumorportal-CDK18 »
COSMIC-CDK18 »
GenomeRNAi-CDK18 »
Genecards-CDK18


Protein-protein Interactions for CDK18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK18 Cat. description Hein, Mann, Cell 2015
Category members IP bait MASTL Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCBP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFXN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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