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Query: CDK17

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK17 0 1.502 1.060 -0.600
CDK17 0 1.502 1.060 -0.600 -0.510 0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK17 Ubiquitylation K143 0.747 _ISMEDLNK(gl)R_
CDK17 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK17 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK17 Phosphorylation S9 0.208 0.548 _RLS(ph)LTLR_
CDK17 Phosphorylation S137 0.529 0.540 _RIS(ph)MEDLNK_
CDK17 Ubiquitylation K243 0.512 _EVSLLK(gl)DLK_
CDK17 Ubiquitylation K221 0.400 _LTENLVALK(gl)EIR_
CDK17 Phosphorylation S165 0.398 _LQINS(ph)PPFDQPMSR_
CDK17 Phosphorylation S180 0.603 0.218 _RAS(ph)LSEIGFGK_
CDK17 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK17 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK17 Phosphorylation S146 -0.051 0.013 _RLS(ph)LPADIR_
CDK17 Ubiquitylation K212 -0.028 _SK(gl)LTENLVALK_
CDK17 Ubiquitylation K499 -0.062 _EIQLQK(gl)DPGFR_
CDK17 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK17 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK17 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK17 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK17 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK17 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK17 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK17 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK17 Phosphorylation S122 0.269 _M(ox)GSDGESDQASGTSSDEVQS(ph)PTGVCLR_

Background Information for CDK17:


Pubmed-CDK17 »
Uniprot-CDK17 »
Biogrid-CDK17 »
ProteomicsDB-CDK17 »

Tumorportal-CDK17 »
COSMIC-CDK17 »
GenomeRNAi-CDK17 »
Genecards-CDK17


Protein-protein Interactions for CDK17
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UNC45A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK17
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK17
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK17
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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