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Query: CDK14

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK14 0 0.876 -0.020 0.360 -0.510 0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK14 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK14 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK14 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK14 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK14 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK14 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK14 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDK14 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK14 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK14 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK14 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK14 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_

Background Information for CDK14:


Pubmed-CDK14 »
Uniprot-CDK14 »
Biogrid-CDK14 »
ProteomicsDB-CDK14 »

Tumorportal-CDK14 »
COSMIC-CDK14 »
GenomeRNAi-CDK14 »
Genecards-CDK14


Protein-protein Interactions for CDK14
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDKL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK14
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0030332 cyclin binding Database 0
Category members GO Category GO:0060828 regulation of canonical Wnt signaling pathway Database 0


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