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Query: CDK11A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CDK11A 0 4.478 -0.340 0.640 0.520 0.139 1.329 0.365 0.320
CDK11A 0 4.478 0.040 -0.200 0.520 0.139 1.329 0.365 0.320

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CDK11A Phosphorylation T61 0.721 _MEIT(ph)IRNSPYR_
CDK11A Phosphorylation S589 0.529 0.585 _EYGS(ph)PLKAYT(ph)PVVVTLWYR_
CDK11A Phosphorylation S47 0.375 0.573 _RDS(ph)LEEGELR_
CDK11A Phosphorylation S65 0.730 0.552 _MEITIRNS(ph)PYR_
CDK11A Phosphorylation S283 0.324 0.483 _DLLSDLQDIS(ph)DSER_
CDK11A Phosphorylation T595 0.472 0.397 _AYT(ph)PVVVTLWYR_
CDK11A Ubiquitylation K467 -0.286 _TDEIVALK(gl)R_
CDK11A Phosphorylation T751 -0.349 -0.460 _RGT(ph)SPRPPEGGLGYSQLGDDDLK_
CDK11A Phosphorylation S752 -0.526 -0.643 _RGTS(ph)PRPPEGGLGYSQLGDDDLK_
CDK11A Ubiquitylation K719 -0.672 _ISAEDGLK(gl)HEYFR_
CDK11A Phosphorylation S234 -0.737 -0.712 _S(ph)PPRPPR_
CDK11A Ubiquitylation K672 -1.465 _IWPGYSELPAVK(gl)K_
CDK11A Ubiquitylation K673 -1.465 _IWPGYSELPAVK(gl)K_

Background Information for CDK11A:


Pubmed-CDK11A »
Uniprot-CDK11A »
Biogrid-CDK11A »
ProteomicsDB-CDK11A »

Tumorportal-CDK11A »
COSMIC-CDK11A »
GenomeRNAi-CDK11A »
Genecards-CDK11A


Protein-protein Interactions for CDK11A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CDK11A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring CDK11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CDK11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members Pathway Pathway_960 BIOCARTA_HIVNEF_PATHWAY 0 0.17
Category members GO Category GO:0004693 cyclin-dependent protein serine/threonine kinase activity Database 0.08
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0001558 regulation of cell growth Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0050684 regulation of mRNA processing Database 0


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