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Query: CD58

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD58 0 -0.023 0.550 -0.430

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD58 Ubiquitylation K78 -0.023 _AFSSFK(gl)NR_

Background Information for CD58:





Protein-protein Interactions for CD58

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABHD12B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CD58

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CD58

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CD58

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0031225 anchored to membrane Database 1.36
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members Pathway Pathway_1221 BIOCARTA_IL17_PATHWAY 0 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0


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