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Query: CD46

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CD46 0 0.509 0.540 -0.870

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CD46 Ubiquitylation K245 0.509 _QISGFGKK(gl)_
CD46 Ubiquitylation K224 -0.397 _AAPECK(gl)VVK_

Background Information for CD46:


Pubmed-CD46 »
Uniprot-CD46 »
Biogrid-CD46 »
ProteomicsDB-CD46 »

Tumorportal-CD46 »
COSMIC-CD46 »
GenomeRNAi-CD46 »
Genecards-CD46


Protein-protein Interactions for CD46
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TRIM16L Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CD46
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Sushi_SCR_CCP IPR000436 0


Protein complexes (CORUM database) featuring CD46
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CD46
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members Pathway Pathway_1189 KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 0 0
Category members Pathway Pathway_1297 REACTOME_COMPLEMENT_CASCADE 0 0
Category members Pathway Pathway_1302 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE 0 0
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0001848 complement binding Database 0
Category members GO Category GO:0002079 inner acrosomal membrane Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0006958 complement activation, classical pathway Database 0
Category members GO Category GO:0007338 single fertilization Database 0
Category members GO Category GO:0030449 regulation of complement activation Database 0
Category members GO Category GO:0045916 negative regulation of complement activation Database 0


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