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Query: CBFA2T3

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CBFA2T3 0 1.513 -0.750 1.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CBFA2T3 Ubiquitylation K489 0.393 _K(gl)AEEAVNEVK_

Background Information for CBFA2T3:


Pubmed-CBFA2T3 »
Uniprot-CBFA2T3 »
Biogrid-CBFA2T3 »
ProteomicsDB-CBFA2T3 »

Tumorportal-CBFA2T3 »
COSMIC-CBFA2T3 »
GenomeRNAi-CBFA2T3 »
Genecards-CBFA2T3


Protein-protein Interactions for CBFA2T3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRDM14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CBFA2T3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_MYND IPR002893 0.06
Category members TAFH_NHR1 IPR003894 0
Category members ETO IPR013289 0
Category members NHR2 IPR014896 0


Protein complexes (CORUM database) featuring CBFA2T3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CBFA2T3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members Pathway Pathway_609 PID_ERBB4_PATHWAY 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030851 granulocyte differentiation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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