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Query: CAPZA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CAPZA1 0 -1.206 0.560 -0.680
CAPZA1 0 -1.206 0.560 -0.680 -0.049 -0.077 0.058 0.155 -0.264

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CAPZA1 Phosphorylation S9 0.754 0.930 _(ac)ADFDDRVS(ph)DEEKVR_
CAPZA1 Ubiquitylation K118 -1.483 -1.231 _EASDPQPEEADGGLK(gl)SWR_

Background Information for CAPZA1:


Pubmed-CAPZA1 »
Uniprot-CAPZA1 »
Biogrid-CAPZA1 »
ProteomicsDB-CAPZA1 »

Tumorportal-CAPZA1 »
COSMIC-CAPZA1 »
GenomeRNAi-CAPZA1 »
Genecards-CAPZA1


Protein-protein Interactions for CAPZA1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait CALML3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN4 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO5C Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDH7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNKS1BP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3KBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CAPZA1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CapZ_alpha IPR002189 0.01


Protein complexes (CORUM database) featuring CAPZA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CAPZA1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0008290 F-actin capping protein complex Database 1.36
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0071203 WASH complex Database 0.31
Category members Pathway Pathway_460 REACTOME_INNATE_IMMUNE_SYSTEM 0 0.29
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members Pathway Pathway_457 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING 0 0.04
Category members GO Category GO:0051693 actin filament capping Database 0


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