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Query: CABLES1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CABLES1 1 4.171 -1.170 2.570

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CABLES1 Phosphorylation T415 0.987 _RNT(ph)IDSTSSFSQFR_
CABLES1 Phosphorylation S291 0.614 0.568 _SS(ph)LETLEDIEENAPLRR_
CABLES1 Phosphorylation S290 0.347 0.381 _S(ph)SLETLEDIEENAPLRR_

Background Information for CABLES1:


Pubmed-CABLES1 »
Uniprot-CABLES1 »
Biogrid-CABLES1 »
ProteomicsDB-CABLES1 »

Tumorportal-CABLES1 »
COSMIC-CABLES1 »
GenomeRNAi-CABLES1 »
Genecards-CABLES1


Protein-protein Interactions for CABLES1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FIBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GOPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CABLES1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclin_N IPR006671 0
Category members Cdk5/c-Abl_linker_Cables IPR012388 0
Category members Cyclin-like IPR013763 0


Protein complexes (CORUM database) featuring CABLES1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CABLES1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members Pathway Pathway_208 PID_TAP63_PATHWAY 0 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity Database 0
Category members GO Category GO:0051302 regulation of cell division Database 0


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