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Query: C14ORF166

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
C14orf166 1 -1.468 3.240 -1.010 -0.192 -0.333 0.294 -0.362 -0.198

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
C14orf166 Ubiquitylation K108 -0.336 -0.565 _YKDLVPDNSK(gl)TADNATK_
C14orf166 Ubiquitylation K171 -0.164 _LTQDAVAK(gl)ANQTK_
C14orf166 Ubiquitylation K176 -0.152 _ANQTK(gl)EGLPVALDK_

Background Information for C14orf166:


Pubmed-C14orf166 »
Uniprot-C14orf166 »
Biogrid-C14orf166 »
ProteomicsDB-C14orf166 »

Tumorportal-C14orf166 »
COSMIC-C14orf166 »
GenomeRNAi-C14orf166 »
Genecards-C14orf166


Protein-protein Interactions for C14orf166
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MCM3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015


Protein Domains in C14orf166
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring C14orf166
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring C14orf166
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0000993 RNA polymerase II core binding Database 0.91
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13


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