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Query: BCS1L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BCS1L 1 -0.554 -1.580 2.960
BCS1L 1 -0.554 -1.580 2.960 -0.251 0.013

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BCS1L Ubiquitylation K300 -1.879 -1.397 _DLAVENPVK(gl)YQGLGR_

Background Information for BCS1L:


Pubmed-BCS1L »
Uniprot-BCS1L »
Biogrid-BCS1L »
ProteomicsDB-BCS1L »

Tumorportal-BCS1L »
COSMIC-BCS1L »
GenomeRNAi-BCS1L »
Genecards-BCS1L


Protein-protein Interactions for BCS1L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26A Cat. description Hein, Mann, Cell 2015
Category members IP bait IMPDH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MATN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBLAC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEFF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM128 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VCAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BCS1L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14


Protein complexes (CORUM database) featuring BCS1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BCS1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0033617 mitochondrial respiratory chain complex IV assembly Database 0.2
Category members GO Category GO:0003724 RNA helicase activity Database 0.07
Category members GO Category GO:0005750 mitochondrial respiratory chain complex III Database 0.07
Category members GO Category GO:0032981 mitochondrial respiratory chain complex I assembly Database 0.04
Category members Disease phenotype Isolated_CoQ-cytochrome_C_reductase_deficiency Isolated CoQ-cytochrome C reductase deficiency Database 0
Category members Disease phenotype Leigh_syndrome_with_nephrotic_syndrome Leigh syndrome with nephrotic syndrome Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0034551 mitochondrial respiratory chain complex III assembly Database 0


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