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Query: BCL7A

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
BCL7A 0 -1.979 0.090 -0.140 -0.788 0.902 0.438 -1.658 -0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
BCL7A Ubiquitylation K27 0.587 _VMAAIEK(gl)VR_

Background Information for BCL7A:


Pubmed-BCL7A »
Uniprot-BCL7A »
Biogrid-BCL7A »
ProteomicsDB-BCL7A »

Tumorportal-BCL7A »
COSMIC-BCL7A »
GenomeRNAi-BCL7A »
Genecards-BCL7A


Protein-protein Interactions for BCL7A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAPK8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIPIN Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in BCL7A
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring BCL7A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring BCL7A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0005575 cellular_component Database 0


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