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Query: ASCC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASCC1 0 0.723 1.460 -0.840 -0.235 -0.305

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ASCC1 Ubiquitylation K335 1.263 _YNLYTAEGKYIFK(gl)_

Background Information for ASCC1:


Pubmed-ASCC1 »
Uniprot-ASCC1 »
Biogrid-ASCC1 »
ProteomicsDB-ASCC1 »

Tumorportal-ASCC1 »
COSMIC-ASCC1 »
GenomeRNAi-ASCC1 »
Genecards-ASCC1


Protein-protein Interactions for ASCC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AURKA Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait PABPC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait ALKBH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASCC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13
Category members RNA_ligase/cNuc_Pdiesterase IPR009097 0.04
Category members Kinase-A_anchor_nucl_local_sig IPR019510 0


Protein complexes (CORUM database) featuring ASCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1377 hASC-1 complex Database 0.47


Categories featuring ASCC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Disease phenotype BARRETT_ESOPHAGUS BARRETT ESOPHAGUS Database 0.04
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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