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Query: ARHGAP5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGAP5 0 1.870 -0.150 0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGAP5 Phosphorylation S765 1.073 _HNLDVVS(ph)PIPANK_
ARHGAP5 Phosphorylation T1217 0.497 0.807 _GGIDNPAIT(ph)SDQELDDKK_
ARHGAP5 Phosphorylation S1218 0.377 0.527 _GGIDNPAITS(ph)DQELDDKK_

Background Information for ARHGAP5:


Pubmed-ARHGAP5 »
Uniprot-ARHGAP5 »
Biogrid-ARHGAP5 »
ProteomicsDB-ARHGAP5 »

Tumorportal-ARHGAP5 »
COSMIC-ARHGAP5 »
GenomeRNAi-ARHGAP5 »
Genecards-ARHGAP5


Protein-protein Interactions for ARHGAP5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMURF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGAP5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members FF_domain IPR002713 1.23
Category members Small_GTPase IPR001806 0.65
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members RhoGAP_dom IPR000198 0


Protein complexes (CORUM database) featuring ARHGAP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARHGAP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members Pathway Pathway_669 PID_RAC1_PATHWAY 0 0.68
Category members Pathway Pathway_677 BIOCARTA_MYOSIN_PATHWAY 0 0.53
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members Pathway Pathway_536 BIOCARTA_ECM_PATHWAY 0 0.25
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0008361 regulation of cell size Database 0.06
Category members Pathway Pathway_966 BIOCARTA_D4GDI_PATHWAY 0 0
Category members GO Category GO:0002053 positive regulation of mesenchymal cell proliferation Database 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0030879 mammary gland development Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0
Category members GO Category GO:0042169 SH2 domain binding Database 0


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