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Query: ARHGAP12

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGAP12 0 -0.830 -0.240 -0.040

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGAP12 Phosphorylation T174 -0.246 _T(ph)RSFGHFPGPEFLDVEK_
ARHGAP12 Phosphorylation S176 -0.544 -0.246 _S(ph)FGHFPGPEFLDVEK_
ARHGAP12 Phosphorylation T231 -0.622 _ATT(ph)PPNQGRPDS(ph)PVYANLQELK_
ARHGAP12 Phosphorylation S240 -0.622 _ATT(ph)PPNQGRPDS(ph)PVYANLQELK_

Background Information for ARHGAP12:


Pubmed-ARHGAP12 »
Uniprot-ARHGAP12 »
Biogrid-ARHGAP12 »
ProteomicsDB-ARHGAP12 »

Tumorportal-ARHGAP12 »
COSMIC-ARHGAP12 »
GenomeRNAi-ARHGAP12 »
Genecards-ARHGAP12


Protein-protein Interactions for ARHGAP12
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGAP12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGAP12
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WW_dom IPR001202 1.15
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members PH_domain IPR001849 0.14
Category members RhoGAP_dom IPR000198 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring ARHGAP12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARHGAP12
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0007165 signal transduction Database 0


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