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Query: ARHGAP10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGAP10 0 -2.147 0.320 -0.130

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGAP10 Phosphorylation S591 -0.697 -1.450 _TPPDTTFPEPTCLSAS(ph)PPNAPPR_

Background Information for ARHGAP10:


Pubmed-ARHGAP10 »
Uniprot-ARHGAP10 »
Biogrid-ARHGAP10 »
ProteomicsDB-ARHGAP10 »

Tumorportal-ARHGAP10 »
COSMIC-ARHGAP10 »
GenomeRNAi-ARHGAP10 »
Genecards-ARHGAP10


Protein-protein Interactions for ARHGAP10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGAP26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2CD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGAP10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members PH_domain IPR001849 0.14
Category members SH3_2 IPR011511 0.08
Category members RhoGAP_dom IPR000198 0
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring ARHGAP10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5274 Cell-cell junction complex (ARHGAP10-CTNNA1) Database 0


Categories featuring ARHGAP10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_795 REACTOME_REGULATION_OF_APOPTOSIS 0 0.31
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0


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