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Query: ARHGAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARHGAP1 0 2.635 0.280 0.190

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARHGAP1 Phosphorylation S50 1.380 1.255 _SS(ph)SPELVTHLK_
ARHGAP1 Phosphorylation S51 1.221 1.064 _SSS(ph)PELVTHLK_

Background Information for ARHGAP1:


Pubmed-ARHGAP1 »
Uniprot-ARHGAP1 »
Biogrid-ARHGAP1 »
ProteomicsDB-ARHGAP1 »

Tumorportal-ARHGAP1 »
COSMIC-ARHGAP1 »
GenomeRNAi-ARHGAP1 »
Genecards-ARHGAP1


Protein-protein Interactions for ARHGAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARHGAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members RhoGAP_dom IPR000198 0
Category members CRAL-TRIO_dom IPR001251 0


Protein complexes (CORUM database) featuring ARHGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARHGAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members Pathway Pathway_510 SIG_CHEMOTAXIS 0 0.28
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members Pathway Pathway_1157 PID_RAC1_REG_PATHWAY 0 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007266 Rho protein signal transduction Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030675 Rac GTPase activator activity Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0
Category members GO Category GO:0032855 positive regulation of Rac GTPase activity Database 0
Category members GO Category GO:0043087 regulation of GTPase activity Database 0


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