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Query: ARFGEF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARFGEF1 0 -0.114

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARFGEF1 Phosphorylation S52 -0.014 -0.100 _AETEKQS(ph)PPHGEAK_
ARFGEF1 Phosphorylation T48 -0.052 -0.113 _ACEVALEEIKAET(ph)EKQSPPHGEAK_

Background Information for ARFGEF1:


Pubmed-ARFGEF1 »
Uniprot-ARFGEF1 »
Biogrid-ARFGEF1 »
ProteomicsDB-ARFGEF1 »

Tumorportal-ARFGEF1 »
COSMIC-ARFGEF1 »
GenomeRNAi-ARFGEF1 »
Genecards-ARFGEF1


Protein-protein Interactions for ARFGEF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CSGALNACT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDNRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPY2R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRIG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCL1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARFGEF1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Sec7_dom IPR000904 0
Category members DUF1981_Sec7_assoc IPR015403 0


Protein complexes (CORUM database) featuring ARFGEF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARFGEF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_709 BIOCARTA_ARAP_PATHWAY 0 0.76
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0030532 small nuclear ribonucleoprotein complex Database 0.15
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members GO Category GO:0007030 Golgi organization Database 0.13
Category members GO Category GO:0030837 negative regulation of actin filament polymerization Database 0.13
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0005086 ARF guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0010256 endomembrane system organization Database 0
Category members GO Category GO:0017022 myosin binding Database 0
Category members GO Category GO:0032012 regulation of ARF protein signal transduction Database 0
Category members GO Category GO:0034237 protein kinase A regulatory subunit binding Database 0
Category members GO Category GO:0034259 negative regulation of Rho GTPase activity Database 0


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