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Query: ARAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARAP1 1 2.254 -1.730 2.580 -0.455 -0.098

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARAP1 Ubiquitylation K586 0.227 _GLGAGVSK(gl)VR_

Background Information for ARAP1:


Pubmed-ARAP1 »
Uniprot-ARAP1 »
Biogrid-ARAP1 »
ProteomicsDB-ARAP1 »

Tumorportal-ARAP1 »
COSMIC-ARAP1 »
GenomeRNAi-ARAP1 »
Genecards-ARAP1


Protein-protein Interactions for ARAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait HMG2L1;HMGXB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3KBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members PH_domain IPR001849 0.14
Category members Ras-assoc IPR000159 0
Category members RhoGAP_dom IPR000198 0
Category members ArfGAP IPR001164 0
Category members SAM IPR001660 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring ARAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0005802 trans-Golgi network Database 0.13
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding Database 0.04
Category members GO Category GO:0001921 positive regulation of receptor recycling Database 0.02
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0005100 Rho GTPase activator activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008060 ARF GTPase activator activity Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0031702 type 1 angiotensin receptor binding Database 0
Category members GO Category GO:0032312 regulation of ARF GTPase activity Database 0
Category members GO Category GO:0032580 Golgi cisterna membrane Database 0
Category members GO Category GO:0043089 positive regulation of Cdc42 GTPase activity Database 0
Category members GO Category GO:0051270 regulation of cellular component movement Database 0
Category members GO Category GO:0051491 positive regulation of filopodium assembly Database 0
Category members GO Category GO:0051497 negative regulation of stress fiber assembly Database 0


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