bioLOGIC-db

bioLOGIC Data

Query: APOL2

This is a cancer-associated gene according to the Broad cancer gene census.

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
APOL2	0	-0.092	0.320	-0.410

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
APOL2	Ubiquitylation	K305	0.315	-0.407	_NLDQSGTNVAK(gl)VMK_

ProteomicsDB-APOL2 »

Protein-protein Interactions for APOL2

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait APOL2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait CERK	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ID2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait MAPK3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NCBP1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait POLK	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TMEM63B	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TUBA3C;TUBA3E	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait APBB2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CHRNA3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CHRND	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ERAP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait GBP5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HTR3A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PSG9	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in APOL2

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ApoL	IPR008405	0

Protein complexes (CORUM database) featuring APOL2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring APOL2

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005576	extracellular region	Database	10.9
Category members	GO Category	GO:0005789	endoplasmic reticulum membrane	Database	1.57
Category members	Human mutations	Broad_cancer_genes	Broad cancer genes (Lawrence et al., 2014)	literature	1.14
Category members	GO Category	GO:0007275	multicellular organismal development	Database	0.31
Category members	GO Category	GO:0008203	cholesterol metabolic process	Database	0.08
Category members	GO Category	GO:0005102	receptor binding	Database	0
Category members	GO Category	GO:0006629	lipid metabolic process	Database	0
Category members	GO Category	GO:0006869	lipid transport	Database	0
Category members	GO Category	GO:0006953	acute-phase response	Database	0
Category members	GO Category	GO:0008035	high-density lipoprotein particle binding	Database	0
Category members	GO Category	GO:0008289	lipid binding	Database	0
Category members	GO Category	GO:0042157	lipoprotein metabolic process	Database	0
Category members	GO Category	GO:0060135	maternal process involved in female pregnancy	Database	0