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Query: API5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
API5 0 1.521 0.700 -0.330 -0.188 1.122 -2.174 0.074 0.305

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
API5 Ubiquitylation K153 1.162 _AIK(gl)FLSTK_
API5 Phosphorylation S464 0.169 0.234 _RASEDTTSGS(ph)PPK_
API5 Ubiquitylation K36 -0.455 _DAYQVILDGVK(gl)GGTK_
API5 Ubiquitylation K40 -0.455 _DAYQVILDGVK(gl)GGTK_
API5 Ubiquitylation K180 0.817 _EVEELILTESK(gl)K_
API5 Ubiquitylation K181 0.817 _EVEELILTESK(gl)K_

Background Information for API5:





Protein-protein Interactions for API5

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait EZH2 Cat. description Hein, Mann, Cell 2015


Protein Domains in API5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring API5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99
Category members Corum 1069 FIF-FGR2 complex Database 0.17


Categories featuring API5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0017134 fibroblast growth factor binding Database 0


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