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Query: ANKFY1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ANKFY1 1 6.547 -1.490 2.580 1.288 0.595 0.226 1.027

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ANKFY1 Ubiquitylation K858 -0.208 0.547 _SAEAILK(gl)R_
ANKFY1 Ubiquitylation K937 0.284 _VNELTK(gl)HR_

Background Information for ANKFY1:


Pubmed-ANKFY1 »
Uniprot-ANKFY1 »
Biogrid-ANKFY1 »
ProteomicsDB-ANKFY1 »

Tumorportal-ANKFY1 »
COSMIC-ANKFY1 »
GenomeRNAi-ANKFY1 »
Genecards-ANKFY1


Protein-protein Interactions for ANKFY1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKFY1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIF1AN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ANKFY1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members BTB/POZ-like IPR000210 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32
Category members Znf_FYVE IPR000306 0
Category members Ankyrin_rpt IPR002110 0
Category members Znf_FYVE-rel IPR017455 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring ANKFY1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ANKFY1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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