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Query: ALDH7A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALDH7A1 0 2.855 -1.400 2.320 0.605 -1.569 1.140 1.119

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALDH7A1 Ubiquitylation K537 -0.899 _DLPLAQGIK(gl)FQ_
ALDH7A1 Ubiquitylation K352 0.139 _K(gl)AYAQIR_

Background Information for ALDH7A1:


Pubmed-ALDH7A1 »
Uniprot-ALDH7A1 »
Biogrid-ALDH7A1 »
ProteomicsDB-ALDH7A1 »

Tumorportal-ALDH7A1 »
COSMIC-ALDH7A1 »
GenomeRNAi-ALDH7A1 »
Genecards-ALDH7A1


Protein-protein Interactions for ALDH7A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ERP44 Cat. description Hein, Mann, Cell 2015
Category members IP bait KBTBD7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF2A Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIA Cat. description Hein, Mann, Cell 2015
Category members IP bait C14orf149 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait XRCC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALDH7A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldehyde_DH_dom IPR015590 0
Category members Ald_DH/histidinol_DH IPR016161 0


Protein complexes (CORUM database) featuring ALDH7A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALDH7A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members Pathway Pathway_136 KEGG_LIMONENE_AND_PINENE_DEGRADATION 0 0.87
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members Pathway Pathway_134 KEGG_BETA_ALANINE_METABOLISM 0 0.49
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members Pathway Pathway_37 KEGG_TRYPTOPHAN_METABOLISM 0 0.06
Category members GO Category GO:0006081 cellular aldehyde metabolic process Database 0.05
Category members Pathway Pathway_19 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members Pathway Pathway_137 KEGG_HISTIDINE_METABOLISM 0 0
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members Pathway Pathway_83 KEGG_ASCORBATE_AND_ALDARATE_METABOLISM 0 0
Category members GO Category GO:0004029 aldehyde dehydrogenase (NAD) activity Database 0
Category members GO Category GO:0006554 lysine catabolic process Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Database 0
Category members GO Category GO:0019285 glycine betaine biosynthetic process from choline Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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