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Query: ALDH5A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALDH5A1 0 3.018 1.110 -0.930 0.317 1.095 -0.202 0.644 1.164

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ALDH5A1:


Pubmed-ALDH5A1 »
Uniprot-ALDH5A1 »
Biogrid-ALDH5A1 »
ProteomicsDB-ALDH5A1 »

Tumorportal-ALDH5A1 »
COSMIC-ALDH5A1 »
GenomeRNAi-ALDH5A1 »
Genecards-ALDH5A1


Protein-protein Interactions for ALDH5A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C17orf90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf85 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALDH5A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldehyde_DH_dom IPR015590 0
Category members Ald_DH/histidinol_DH IPR016161 0


Protein complexes (CORUM database) featuring ALDH5A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALDH5A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0009448 gamma-aminobutyric acid metabolic process Database 0.32
Category members GO Category GO:0006105 succinate metabolic process Database 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0009450 gamma-aminobutyric acid catabolic process Database 0.11
Category members GO Category GO:0006650 glycerophospholipid metabolic process Database 0.07
Category members Pathway Pathway_389 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION 0 0.04
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members GO Category GO:0006536 glutamate metabolic process Database 0.01
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_390 REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE 0 0
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members GO Category GO:0006678 glucosylceramide metabolic process Database 0
Category members GO Category GO:0006681 galactosylceramide metabolic process Database 0
Category members GO Category GO:0006749 glutathione metabolic process Database 0
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0042135 neurotransmitter catabolic process Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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