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Query: ALDH2

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALDH2 0 2.217 -0.950 0.830 -0.471 1.226 -1.386 0.748 1.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ALDH2:


Pubmed-ALDH2 »
Uniprot-ALDH2 »
Biogrid-ALDH2 »
ProteomicsDB-ALDH2 »

Tumorportal-ALDH2 »
COSMIC-ALDH2 »
GenomeRNAi-ALDH2 »
Genecards-ALDH2


Protein-protein Interactions for ALDH2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALDH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALDH2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldehyde_DH_dom IPR015590 0
Category members Ald_DH/histidinol_DH IPR016161 0


Protein complexes (CORUM database) featuring ALDH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALDH2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members Pathway Pathway_136 KEGG_LIMONENE_AND_PINENE_DEGRADATION 0 0.87
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members Pathway Pathway_134 KEGG_BETA_ALANINE_METABOLISM 0 0.49
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_37 KEGG_TRYPTOPHAN_METABOLISM 0 0.06
Category members Pathway Pathway_19 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_DEGRADATION 0 0.04
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members Pathway Pathway_137 KEGG_HISTIDINE_METABOLISM 0 0
Category members Pathway Pathway_138 REACTOME_ETHANOL_OXIDATION 0 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_141 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS 0 0
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members Pathway Pathway_83 KEGG_ASCORBATE_AND_ALDARATE_METABOLISM 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0004029 aldehyde dehydrogenase (NAD) activity Database 0
Category members GO Category GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity Database 0
Category members GO Category GO:0006066 alcohol metabolic process Database 0
Category members GO Category GO:0006068 ethanol catabolic process Database 0
Category members GO Category GO:0006069 ethanol oxidation Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0042136 neurotransmitter biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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