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Query: ALDH18A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALDH18A1 1 4.099 -1.600 2.800 0.974 0.304 -0.876 0.434 0.463

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ALDH18A1:


Pubmed-ALDH18A1 »
Uniprot-ALDH18A1 »
Biogrid-ALDH18A1 »
ProteomicsDB-ALDH18A1 »

Tumorportal-ALDH18A1 »
COSMIC-ALDH18A1 »
GenomeRNAi-ALDH18A1 »
Genecards-ALDH18A1


Protein-protein Interactions for ALDH18A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CERK Cat. description Hein, Mann, Cell 2015
Category members IP bait DCP1A Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait LLGL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBGCP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RALB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALDH18A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldehyde_DH_dom IPR015590 0
Category members Ald_DH/histidinol_DH IPR016161 0


Protein complexes (CORUM database) featuring ALDH18A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALDH18A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members GO Category GO:0006536 glutamate metabolic process Database 0.01
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_394 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION 0 0
Category members GO Category GO:0006561 proline biosynthetic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008652 cellular amino acid biosynthetic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0019240 citrulline biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0055129 L-proline biosynthetic process Database 0


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