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Query: ALCAM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALCAM 0 2.803 0.270 -0.290
ALCAM 0 2.803 0.270 -0.290 0.038 0.639

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALCAM Ubiquitylation K572 1.248 0.878 _DLGNMEENK(gl)K_

Background Information for ALCAM:


Pubmed-ALCAM »
Uniprot-ALCAM »
Biogrid-ALCAM »
ProteomicsDB-ALCAM »

Tumorportal-ALCAM »
COSMIC-ALCAM »
GenomeRNAi-ALCAM »
Genecards-ALCAM


Protein-protein Interactions for ALCAM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALCAM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait APOD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDH12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALCAM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ig-like_dom IPR007110 0.6
Category members Ig_sub IPR003599 0.43
Category members Ig_sub2 IPR003598 0.21
Category members Ig_V-set IPR013106 0.09
Category members Ig_V-set_subgr IPR003596 0
Category members CD80_C2-set IPR013162 0


Protein complexes (CORUM database) featuring ALCAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALCAM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_1075 REACTOME_L1CAM_INTERACTIONS 0 1.32
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_1217 KEGG_CELL_ADHESION_MOLECULES_CAMS 0 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008045 motor neuron axon guidance Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0


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