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Query: AKR1A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AKR1A1 0 0.719 1.090 -1.280

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AKR1A1 Ubiquitylation K294 -0.058 _QLNALNK(gl)NWR_
AKR1A1 Ubiquitylation K30 -1.121 _SEPGQVK(gl)AAVK_
AKR1A1 Ubiquitylation K308 0.778 _YIVPMLTVDGK(gl)R_

Background Information for AKR1A1:


Pubmed-AKR1A1 »
Uniprot-AKR1A1 »
Biogrid-AKR1A1 »
ProteomicsDB-AKR1A1 »

Tumorportal-AKR1A1 »
COSMIC-AKR1A1 »
GenomeRNAi-AKR1A1 »
Genecards-AKR1A1


Protein-protein Interactions for AKR1A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKR1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AKR1A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldo/keto_reductase_subgr IPR020471 0
Category members NADP_OxRdtase_dom IPR023210 0


Protein complexes (CORUM database) featuring AKR1A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AKR1A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_71 KEGG_GLYCEROLIPID_METABOLISM 0 0.45
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0006081 cellular aldehyde metabolic process Database 0.05
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members GO Category GO:0004032 alditol:NADP+ 1-oxidoreductase activity Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0019853 L-ascorbic acid biosynthetic process Database 0
Category members GO Category GO:0046185 aldehyde catabolic process Database 0


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