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Query: AK4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AK4 0 -0.088 -0.090 0.170
AK4 0 -0.088 -0.090 0.170 0.683
AK4 0 -0.088 -0.030 0.550
AK4 0 -0.088 -0.030 0.550 0.683

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AK4 Ubiquitylation K3 -1.321 _(ac)AK(gl)QYIEK_

Background Information for AK4:


Pubmed-AK4 »
Uniprot-AK4 »
Biogrid-AK4 »
ProteomicsDB-AK4 »

Tumorportal-AK4 »
COSMIC-AK4 »
GenomeRNAi-AK4 »
Genecards-AK4


Protein-protein Interactions for AK4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATF6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C17orf90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AK4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Adenylat/UMP-CMP_kin IPR000850 0
Category members Adenyl_kin_sub IPR006259 0
Category members Adenylate_kinase_lid-dom IPR007862 0


Protein complexes (CORUM database) featuring AK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0001889 liver development Database 0.51
Category members Pathway Pathway_68 KEGG_PURINE_METABOLISM 0 0.23
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0004017 adenylate kinase activity Database 0
Category members GO Category GO:0004550 nucleoside diphosphate kinase activity Database 0
Category members GO Category GO:0006165 nucleoside diphosphate phosphorylation Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0009142 nucleoside triphosphate biosynthetic process Database 0
Category members GO Category GO:0016776 phosphotransferase activity, phosphate group as acceptor Database 0
Category members GO Category GO:0046033 AMP metabolic process Database 0
Category members GO Category GO:0046034 ATP metabolic process Database 0
Category members GO Category GO:0046039 GTP metabolic process Database 0
Category members GO Category GO:0046899 nucleoside triphosphate adenylate kinase activity Database 0


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