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Query: AFF4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AFF4 2 -2.612 0.330 0.020 -1.245 -0.478

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AFF4 Phosphorylation S212 2.114 _SKS(ph)PRDPDANWDSPSR_
AFF4 Phosphorylation S836 1.948 2.016 _RTIS(ph)QSSSLK_
AFF4 Phosphorylation S694 0.693 _MFS(ph)PMEEK_
AFF4 Phosphorylation S1043 0.500 0.232 _NSYNNSQAPS(ph)PGLGSK_
AFF4 Phosphorylation S180 0.226 -0.021 _SSS(ph)PGKPQAVSSLNSSHSR_
AFF4 Phosphorylation S671 -0.112 _YPES(ph)NRTPVKPSSVEEEDSFFR_
AFF4 Phosphorylation S487 -0.510 -0.525 _VS(ph)PASSVDSNIPSSQGYK_
AFF4 Phosphorylation S814 -0.345 -0.588 _EKDLLPS(ph)PAGPVPSKDPK_
AFF4 Phosphorylation S1055 -1.035 _AVGMPS(ph)PVSPK_
AFF4 Phosphorylation S1058 -0.975 -1.108 _AVGMPSPVS(ph)PK_
AFF4 Phosphorylation S706 -1.560 _ELLSPLS(ph)EPDDRYPLIVK_
AFF4 Phosphorylation S703 -1.838 _ELLS(ph)PLSEPDDRYPLIVK_
AFF4 Ubiquitylation K363 -0.311 -4.640 _ESQQSNFGTGEQK(gl)R_
AFF4 Ubiquitylation K299 -6.625 _AHLTKLK(gl)_
AFF4 Ubiquitylation K297 -0.843 _AHLTK(gl)LK_
AFF4 Phosphorylation Y668 1.090 _Y(ph)PESNRTPVKPSSVEEEDSFFR_
AFF4 Phosphorylation S679 1.473 _YPESNRTPVKPS(ph)SVEEEDSFFR_

Background Information for AFF4:





Protein-protein Interactions for AFF4

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AFF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLLT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RXRB Cat. description Hein, Mann, Cell 2015
Category members IP bait AFF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AFF4

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TF_AF4/FMR2 IPR007797 0


Protein complexes (CORUM database) featuring AFF4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AFF4

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007286 spermatid development Database 0


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