bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: ADNP

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADNP 0 3.032 0.210 -0.810 -0.684 0.083 0.289 0.229 0.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADNP Phosphorylation S98 0.588 0.952 _NVHS(ph)EDFENR_
ADNP Phosphorylation S953 0.667 _LMHNAS(ph)DSEVDQDDVVEWK_
ADNP Phosphorylation S955 0.656 _LMHNAS(ph)DSEVDQDDVVEWK_
ADNP Ubiquitylation K807 1.120 0.315 _SDIASHFSNK(gl)R_
ADNP Phosphorylation S1071 -0.389 _LSNPQIEWQNSTIDS(ph)EDGEQFDNMTDGVAEPMHGSLAGVK_
ADNP Phosphorylation S709 -0.391 -0.636 _LNQS(ph)PSLAPVK_
ADNP Ubiquitylation K716 -1.904 _LNQSPSLAPVK(gl)R_

Background Information for ADNP:


Pubmed-ADNP »
Uniprot-ADNP »
Biogrid-ADNP »
ProteomicsDB-ADNP »

Tumorportal-ADNP »
COSMIC-ADNP »
GenomeRNAi-ADNP »
Genecards-ADNP


Protein-protein Interactions for ADNP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DAXX Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDHB15 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF644 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POLG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF524 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF581 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADNP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members Homeobox_dom IPR001356 0.63
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring ADNP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADNP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


.

© Copyright Svejstrup Laboratory 2015