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Query: ADD2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ADD2 0 2.308

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ADD2 Phosphorylation S530 0.414 1.091 _SRS(ph)PSTESQLM(ox)SK_
ADD2 Phosphorylation S621 1.217 0.704 _SPLVSPSKS(ph)LEEGTKK_
ADD2 Phosphorylation S613 0.498 0.365 _EAETKS(ph)PLVSPSK_
ADD2 Phosphorylation S592 -0.526 -0.457 _LELDGEKETAPEEPGS(ph)PAK_
ADD2 Phosphorylation S600 -0.697 -0.780 _S(ph)APAS(ph)PVQSPAK_
ADD2 Phosphorylation S596 -1.093 _S(ph)APAS(ph)PVQSPAK_
ADD2 Phosphorylation S11 -1.251 _(ac)SEETVPEAAS(ph)PPPPQGQPYFDR_

Background Information for ADD2:


Pubmed-ADD2 »
Uniprot-ADD2 »
Biogrid-ADD2 »
ProteomicsDB-ADD2 »

Tumorportal-ADD2 »
COSMIC-ADD2 »
GenomeRNAi-ADD2 »
Genecards-ADD2


Protein-protein Interactions for ADD2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ANKRD29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPPA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ADD2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldolase_II/adducin_N IPR001303 0.26


Protein complexes (CORUM database) featuring ADD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ADD2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003779 actin binding Database 5.41
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008290 F-actin capping protein complex Database 1.36
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030507 spectrin binding Database 1.12
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0051017 actin filament bundle assembly Database 0.47
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0051016 barbed-end actin filament capping Database 0.21
Category members GO Category GO:0016023 cytoplasmic membrane-bounded vesicle Database 0.17
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0032092 positive regulation of protein binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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