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Query: ABCC5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCC5 0 -0.453 -0.030 0.180

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCC5 Phosphorylation S509 0.227 _NATLAWDSSHSSIQNS(ph)PK_
ABCC5 Ubiquitylation K961 -0.860 _SPMK(gl)FFDTTPTGR_

Background Information for ABCC5:


Pubmed-ABCC5 »
Uniprot-ABCC5 »
Biogrid-ABCC5 »
ProteomicsDB-ABCC5 »

Tumorportal-ABCC5 »
COSMIC-ABCC5 »
GenomeRNAi-ABCC5 »
Genecards-ABCC5


Protein-protein Interactions for ABCC5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NUPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SESN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRDN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABCC5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members ABC_transptr_TM_dom IPR001140 0.06


Protein complexes (CORUM database) featuring ABCC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members Pathway Pathway_73 REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 0 1.71
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0030203 glycosaminoglycan metabolic process Database 1.44
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_78 REACTOME_HYALURONAN_METABOLISM 0 0.1
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0030212 hyaluronan metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0008514 organic anion transmembrane transporter activity Database 0
Category members GO Category GO:0015711 organic anion transport Database 0
Category members GO Category GO:0030213 hyaluronan biosynthetic process Database 0


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