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Query: ABCB8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCB8 1 -0.161 2.080 -1.250

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCB8 Ubiquitylation K247 -0.161 _QDITFFDANK(gl)TGQLVSR_
ABCB8 Ubiquitylation K573 -0.465 _FGK(gl)LEASDEEVYTAAR_

Background Information for ABCB8:


Pubmed-ABCB8 »
Uniprot-ABCB8 »
Biogrid-ABCB8 »
ProteomicsDB-ABCB8 »

Tumorportal-ABCB8 »
COSMIC-ABCB8 »
GenomeRNAi-ABCB8 »
Genecards-ABCB8


Protein-protein Interactions for ABCB8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKFZp686O24166 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC15A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC1A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPPL2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABCB8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members ABC_transptr_TM_dom IPR001140 0.06


Protein complexes (CORUM database) featuring ABCB8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCB8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members GO Category GO:0043190 ATP-binding cassette (ABC) transporter complex Database 0.01
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0005740 mitochondrial envelope Database 0
Category members GO Category GO:0006810 transport Database 0


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