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Query: ABCB6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCB6 0 -0.036 0.580 -0.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCB6 Ubiquitylation K771 -0.119 0.083 _AIQASLAK(gl)VCANR_

Background Information for ABCB6:


Pubmed-ABCB6 »
Uniprot-ABCB6 »
Biogrid-ABCB6 »
ProteomicsDB-ABCB6 »

Tumorportal-ABCB6 »
COSMIC-ABCB6 »
GenomeRNAi-ABCB6 »
Genecards-ABCB6


Protein-protein Interactions for ABCB6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DPEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNAI2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ABCB6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC1_TM_dom IPR011527 0.33
Category members ABC_transporter-like IPR003439 0.15
Category members ABC_transptr_TM_dom IPR001140 0.06


Protein complexes (CORUM database) featuring ABCB6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCB6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members GO Category GO:0015562 efflux transmembrane transporter activity Database 0.18
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0020037 heme binding Database 0.04
Category members GO Category GO:0043190 ATP-binding cassette (ABC) transporter complex Database 0.01
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members Disease phenotype Colobomatous_microphthalmia Colobomatous microphthalmia Database 0
Category members GO Category GO:0005740 mitochondrial envelope Database 0
Category members GO Category GO:0005774 vacuolar membrane Database 0
Category members GO Category GO:0006779 porphyrin-containing compound biosynthetic process Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0015232 heme transporter activity Database 0
Category members GO Category GO:0015886 heme transport Database 0
Category members GO Category GO:0043588 skin development Database 0
Category members GO Category GO:0070574 cadmium ion transmembrane transport Database 0


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